Steve Carell
Postać: Gru (voice)
Jason Segel
Postać: Vector (voice)
Russell Brand
Postać: Dr. Nefario (voice)
Julie Andrews
Postać: Gru's Mother (voice)
Will Arnett
Postać: Mr. Perkins (voice)
Kristen Wiig
Postać: Miss Hattie (voice)
Miranda Cosgrove
Postać: Margo (voice)
Dana Gaier
Postać: Edith (voice)
Elsie Fisher
Postać: Agnes (voice)
Pierre Coffin
Postać: Tim the Minion / Bob the Minion / Mark the Minion / Phil the Minion / Stuart the Minion (voice)
Chris Renaud
Postać: Dave the Minion (voice)
Jemaine Clement
Postać: Jerry the Minion (voice)
Jack McBrayer
Postać: Carnival Barker / Tourist Dad (voice)
Danny McBride
Postać: Fred McDade (voice)
Mindy Kaling
Postać: Tourist mom (voice)
Rob Huebel
Postać: Anchorman (voice)
Ken Jeong
Postać: Talk Show Host (voice)
Ken Daurio
Postać: Egyptian Guard (voice)
Charles Bright
Postać: Additional Voices (voice)
Katie Leigh
Postać: Additional Voices (voice)
Ranjani Brow
Postać: Additional Voices (voice)
Scott Menville
Postać: Additional Voices (voice)
Holly Dorff
Postać: Additional Voices (voice)
Edie Mirman
Postać: Additional Voices (voice)
Jackie Gonneau
Postać: Additional Voices (voice)
Al Rodrigo
Postać: Additional Voices (voice)
Wendy Hoffman
Postać: Additional Voices (voice)
Jakob Roston
Postać: Additional Voices (voice)
John Hans Tester
Postać: Additional Voices (voice)
Tony Lee
Postać: Additional Voices (voice)
Debi Mae West
Postać: Additional Voices (voice)
James Kyson
Postać: Additional Voices (voice)
Mikaila Baumel
Postać: (voice) (uncredited)
