Steve Carell
Postać: Gru (voice)
Kristen Wiig
Postać: Lucy (voice)
Benjamin Bratt
Postać: Eduardo/ El Macho (voice)
Miranda Cosgrove
Postać: Margo (voice)
Russell Brand
Postać: Dr. Nefario (voice)
Ken Jeong
Postać: Floyd (voice)
Steve Coogan
Postać: Silas (voice)
Elsie Kate Fisher
Postać: Agnes (voice)
Dana Gaier
Postać: Edith (voice)
Moisu00e9s Arias
Postać: Antonio (voice)
Nasim Pedrad
Postać: Jillian (voice)
Kristen Schaal
Postać: Shannon (voice)
Pierre Coffin
Postać: Kevin the Minion / Bob the Minion / Stuart the Minion / Additional Minions / Evil Minions (voice)
Chris Renaud
Postać: Additional Minions / Evil Minions / Italian Waiter (voice)
Nickolai Stoilov
Postać: Arctic Lab Guards (voice)
Vanessa Bayer
Postać: Flight Attendant (voice)
Ava Acres
Postać: Additional Voices (voice)
Lori Alan
Postać: Additional Voices (voice)
Jack Angel
Postać: Additional Voices (voice)
Eva Bella
Postać: Additional Voices (voice)
Georgia Cook
Postać: Additional Voices (voice)
John Cygan
Postać: Additional Voices (voice)
Debi Derryberry
Postać: Additional Voices (voice)
Jess Harnell
Postać: Additional Voices (voice)
Danny Mann
Postać: Additional Voices (voice)
Mona Marshall
Postać: Additional Voices (voice)
Mickie McGowan
Postać: Additional Voices (voice)
Mason McNulty
Postać: Additional Voices (voice)
Alec Medlock
Postać: Additional Voices (voice)
Laraine Newman
Postać: Additional Voices (voice)
Jan Rabson
Postać: Additional Voices (voice)
Andre Robinson
Postać: Additional Voices (voice)
Katie Silverman
Postać: Additional Voices (voice)
Casey Simpson
Postać: Additional Voices (voice)
Claira Nicole Titman
Postać: Additional Voices (voice) (as Claira Titman)
Jim Ward
Postać: Additional Voices (voice) (as James Kevin Ward)
April Winchell
Postać: Additional Voices (voice)
Bailey Gambertoglio
Postać: Little Girl #2 (voice) (uncredited)
Sherry Lynn
Postać: Additional Voices (uncredited)
